An unauthenticated remote attacker could replay SRTP packets which could cause an Asterisk instance configured without strict RTP validation to tear down calls prematurely.
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Asterisk Project Security Advisory - Setting the sip.conf timert1 value to a value higher than 1245 can cause an integer overflow and result in large retransmit timeout times. These large timeout values hold system file descriptors hostage and can cause the system to run out of file descriptors.
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