Wisecracker is an open source high performance distributed cryptanalysis framework that leverages GPUs and multiple CPUs. It allows security researchers to write their own cryptanalysis tools that can distribute brute-force cryptanalysis work across multiple systems with multiple multi-core processors and GPUs. Security researchers can also use the sample tools provided out-of-the-box. The differentiating aspect of Wisecracker is that it uses OpenCL and MPI together to distribute the work across multiple systems, each having multiple CPUs and/or GPUs.
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